The draw for the last 16 of the Europa League was held on Friday, with Arsenal, Atletico Madrid, AC Milan and Borussia Dortmund among the names in the hat.
Milan against Arsenal is the pick of the ties, while Atletico Madrid have been pitted against Lokomotiv Moscow.
Lyon, attempting to reach the final at their Groupama Stadium home in May, take on CSKA Moscow.
The first legs will be played on 8 March, with the return fixtures to take place a week later on 15 March.
Europa League Round of 16 draw in full:
AC Milan vs Arsenal
Lazio vs Dynamo Kiev
RB Leipzig vs Zenit
Atletico Madrid vs Lokomotiv Moscow
CSKA Moscow vs Lyon
Marseille vs Athletic Bilbao
Sporting CP vs Viktoria Plzen
Borussia Dortmund vs Salzburg